Founded in 1983 by the transformation law of the faculty of Sciences and technics of Sfax (founded in 1975) into High School of National Engineering.
The high school of National Engineering of Sfax, had played a major role in the developement of a scientific regional role made up of these institutions :
- Biotechnological center of sfax (CBS)
- Faculty of Sciences of Sfax (FSS)
- Preparatory institute to Engineering studies of Sfax (IPEIS)